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Overexpression of RACGAP1 by E2F1 Promotes Neuroendocrine Differentiation of Prostate Cancer by Stabilizing EZH2 Expression

Neuroendocrine prostate cancer (NEPC) is a lethal subtype of prostate cancer. It is characterized by the loss of androgen receptor (AR) signaling in neuroendocrine transdifferentiation, and finally, resistance to AR-targeted therapy. With the application of a new generation of potent AR inhibitors,...

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Detalles Bibliográficos
Autores principales: Song, Zhengshuai, Cao, Qi, Guo, Bin, Zhao, Ye, Li, Xuechao, Lou, Ning, Zhu, Chenxi, Luo, Gang, Peng, Song, Li, Guohao, Chen, Ke, Wang, Yong, Ruan, Hailong, Guo, Yonglian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529746/
https://www.ncbi.nlm.nih.gov/pubmed/37196108
http://dx.doi.org/10.14336/AD.2023.0202