Pantothenate Kinase 4 Governs Lens Epithelial Fibrosis by Negatively Regulating Pyruvate Kinase M2-Related Glycolysis

Lens fibrosis is one of the leading causes of cataract in the elderly population. The primary energy substrate of the lens is glucose from the aqueous humor, and the transparency of mature lens epithelial cells (LECs) is dependent on glycolysis for ATP. Therefore, the deconstruction of reprogramming...

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Detalles Bibliográficos
Autores principales: Li, Xue, Luo, Lin-Lin, Li, Rui-Feng, Chen, Chun-Lin, Sun, Min, Lin, Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529755/
https://www.ncbi.nlm.nih.gov/pubmed/37196116
http://dx.doi.org/10.14336/AD.2023.0216-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529755/
https://www.ncbi.nlm.nih.gov/pubmed/37196116
http://dx.doi.org/10.14336/AD.2023.0216-1

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