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Pericyte dysfunction and impaired vasomotion are hallmarks of islets during the pathogenesis of type 1 diabetes

Pancreatic islets are endocrine organs that depend on their microvasculature to function. Along with endothelial cells, pericytes comprise the islet microvascular network. These mural cells are crucial for microvascular stability and function, but it is not known if/how they are affected during the...

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Detalles Bibliográficos
Autores principales: Gonçalves, Luciana Mateus, Qadir, Mirza Muhammad Fahd, Boulina, Maria, Makhmutova, Madina, Pereira, Elizabeth, Almaça, Joana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529889/
https://www.ncbi.nlm.nih.gov/pubmed/37531253
http://dx.doi.org/10.1016/j.celrep.2023.112913