The Utility of NGS Analysis in Homologous Recombination Deficiency Tracking

Several tumor types have been efficiently treated with PARP inhibitors (PARPis), which are now approved for the treatment of ovarian, breast, prostate, and pancreatic cancers. The BRCA1/2 genes and mutations in many additional genes involved in the HR pathway may be responsible for the HRD phenomeno...

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Detalles Bibliográficos
Autores principales: Tsantikidi, Aikaterini, Papadopoulou, Eirini, Metaxa-Mariatou, Vasiliki, Kapetsis, George, Tsaousis, Georgios, Meintani, Angeliki, Florou-Chatzigiannidou, Chrysiida, Gazouli, Maria, Papadimitriou, Christos, Timotheadou, Eleni, Kotsakis, Athanasios, Boutis, Anastasios, Boukovinas, Ioannis, Kampletsas, Eleftherios, Kontovinis, Loukas, Fountzilas, Elena, Andreadis, Charalampos, Karanikiotis, Charisios, Filippou, Dimitrios, Theodoropoulos, Georgios, Özdoğan, Mustafa, Nasioulas, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529941/
https://www.ncbi.nlm.nih.gov/pubmed/37761329
http://dx.doi.org/10.3390/diagnostics13182962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529941/
https://www.ncbi.nlm.nih.gov/pubmed/37761329
http://dx.doi.org/10.3390/diagnostics13182962

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