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Mechanical codes of chemical-scale specificity in DNA motifs

In gene transcription, certain sequences of double-stranded (ds)DNA play a vital role in nucleosome positioning and expression initiation. That dsDNA is deformed to various extents in these processes leads us to ask: Could the genomic DNA also have sequence specificity in its chemical-scale mechanic...

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Detalles Bibliográficos
Autores principales: Chen, Yi-Tsao, Yang, Haw, Chu, Jhih-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529945/
https://www.ncbi.nlm.nih.gov/pubmed/37772098
http://dx.doi.org/10.1039/d3sc01671d