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A digital twin reproducing gene regulatory network dynamics of early Ciona embryos indicates robust buffers in the network

How gene regulatory networks (GRNs) encode gene expression dynamics and how GRNs evolve are not well understood, although these problems have been studied extensively. We created a digital twin that accurately reproduces expression dynamics of 13 genes that initiate expression in 32-cell ascidian em...

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Detalles Bibliográficos
Autores principales: Tokuoka, Miki, Satou, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530022/
https://www.ncbi.nlm.nih.gov/pubmed/37756274
http://dx.doi.org/10.1371/journal.pgen.1010953