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A digital twin reproducing gene regulatory network dynamics of early Ciona embryos indicates robust buffers in the network
How gene regulatory networks (GRNs) encode gene expression dynamics and how GRNs evolve are not well understood, although these problems have been studied extensively. We created a digital twin that accurately reproduces expression dynamics of 13 genes that initiate expression in 32-cell ascidian em...
Autores principales: | Tokuoka, Miki, Satou, Yutaka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530022/ https://www.ncbi.nlm.nih.gov/pubmed/37756274 http://dx.doi.org/10.1371/journal.pgen.1010953 |
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