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Programmable RNA-guided DNA endonucleases are widespread in eukaryotes and their viruses

Programmable RNA-guided DNA nucleases perform numerous roles in prokaryotes, but the extent of their spread outside prokaryotes is unclear. Fanzors, the eukaryotic homolog of prokaryotic TnpB proteins, have been detected in genomes of eukaryotes and large viruses, but their activity and functions in...

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Detalles Bibliográficos
Autores principales: Jiang, Kaiyi, Lim, Justin, Sgrizzi, Samantha, Trinh, Michael, Kayabolen, Alisan, Yutin, Natalya, Bao, Weidong, Kato, Kazuki, Koonin, Eugene V., Gootenberg, Jonathan S., Abudayyeh, Omar O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530073/
https://www.ncbi.nlm.nih.gov/pubmed/37756409
http://dx.doi.org/10.1126/sciadv.adk0171