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Programmable RNA-guided DNA endonucleases are widespread in eukaryotes and their viruses
Programmable RNA-guided DNA nucleases perform numerous roles in prokaryotes, but the extent of their spread outside prokaryotes is unclear. Fanzors, the eukaryotic homolog of prokaryotic TnpB proteins, have been detected in genomes of eukaryotes and large viruses, but their activity and functions in...
Autores principales: | Jiang, Kaiyi, Lim, Justin, Sgrizzi, Samantha, Trinh, Michael, Kayabolen, Alisan, Yutin, Natalya, Bao, Weidong, Kato, Kazuki, Koonin, Eugene V., Gootenberg, Jonathan S., Abudayyeh, Omar O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530073/ https://www.ncbi.nlm.nih.gov/pubmed/37756409 http://dx.doi.org/10.1126/sciadv.adk0171 |
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