CHI3L1 signaling impairs hippocampal neurogenesis and cognitive function in autoimmune-mediated neuroinflammation

Chitinase-3–like protein 1 (CHI3L1) is primarily secreted by activated astrocytes in the brain and is known as a reliable biomarker for inflammatory central nervous system (CNS) conditions such as neurodegeneration and autoimmune disorders like neuromyelitis optica (NMO). NMO is an astrocyte disease...

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Detalles Bibliográficos
Autores principales: Jiang, Wei, Zhu, Fan, Xu, Huiming, Xu, Li, Li, Haoyang, Yang, Xin, Khan Afridi, Shabbir, Lai, Shuiqing, Qiu, Xiusheng, Liu, Chunxin, Li, Huilu, Long, Youming, Wang, Yuge, Connolly, Kevin, Elias, Jack A., Lee, Chun Geun, Cui, Yaxiong, Huang, Yu-Wen Alvin, Qiu, Wei, Tang, Changyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530095/
https://www.ncbi.nlm.nih.gov/pubmed/37756391
http://dx.doi.org/10.1126/sciadv.adg8148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530095/
https://www.ncbi.nlm.nih.gov/pubmed/37756391
http://dx.doi.org/10.1126/sciadv.adg8148

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