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Intertumoral lineage diversity and immunosuppressive transcriptional programs in well-differentiated gastroenteropancreatic neuroendocrine tumors

Neuroendocrine tumors (NETs) are rare cancers that most often arise in the gastrointestinal tract and pancreas. The fundamental mechanisms driving gastroenteropancreatic (GEP)–NET growth remain incompletely elucidated; however, the heterogeneous clinical behavior of GEP-NETs suggests that both cellu...

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Detalles Bibliográficos
Autores principales: Hoffman, Samantha E., Dowrey, Todd W., Villacorta Martin, Carlos, Bi, Kevin, Titchen, Breanna, Johri, Shreya, DelloStritto, Laura, Patel, Miraj, Mackichan, Colin, Inga, Stephanie, Chen, Judy, Grimaldi, Grace, Napolitano, Sara, Wakiro, Isaac, Wu, Jingyi, Yeung, Jason, Rotem, Asaf, Sicinska, Ewa, Shannon, Erin, Clancy, Thomas, Wang, Jiping, Denning, Sarah, Brais, Lauren, Besson, Naomi R., Pfaff, Kathleen L., Huang, Ying, Kao, Katrina Z., Rodig, Scott, Hornick, Jason L., Vigneau, Sebastien, Park, Jihye, Kulke, Matthew H., Chan, Jennifer, Van Allen, Eliezer M., Murphy, George J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530100/
https://www.ncbi.nlm.nih.gov/pubmed/37756410
http://dx.doi.org/10.1126/sciadv.add9668