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Piezo1 activates noncanonical EGFR endocytosis and signaling

EGFR-ERK signaling controls cell cycle progression during development, homeostasis, and disease. While EGF ligand and mechanical inputs can activate EGFR-ERK signaling, the molecules linking mechanical force to this axis have remained mysterious. We previously found that stretch promotes mitosis via...

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Detalles Bibliográficos
Autores principales: Pardo-Pastor, Carlos, Rosenblatt, Jody
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530101/
https://www.ncbi.nlm.nih.gov/pubmed/37756411
http://dx.doi.org/10.1126/sciadv.adi1328