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Role of TET1-mediated epigenetic modulation in Alzheimer’s disease

Alzheimer’s disease (AD) is a neurodegenerative disorder influenced by a complex interplay of environmental, epigenetic, and genetic factors. DNA methylation (5mC) and hydroxymethylation (5hmC) are DNA modifications that serve as tissue-specific and temporal regulators of gene expression. TET family...

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Detalles Bibliográficos
Autores principales: Armstrong, Matthew J., Jin, Yulin, Vattathil, Selina M., Huang, Yanting, Schroeder, Jason P., Bennet, David A., Qin, Zhaohui S., Wingo, Thomas S., Jin, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530206/
https://www.ncbi.nlm.nih.gov/pubmed/37562656
http://dx.doi.org/10.1016/j.nbd.2023.106257