Microbiota-produced indole metabolites disrupt mitochondrial function and inhibit Cryptosporidium parvum growth

Cryptosporidiosis is a leading cause of life-threatening diarrhea in young children in resource-poor settings. To explore microbial influences on susceptibility, we screened 85 microbiota-associated metabolites for their effects on Cryptosporidium parvum growth in vitro. We identify eight inhibitory...

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Detalles Bibliográficos
Autores principales: Funkhouser-Jones, Lisa J., Xu, Rui, Wilke, Georgia, Fu, Yong, Schriefer, Lawrence A., Makimaa, Heyde, Rodgers, Rachel, Kennedy, Elizabeth A., VanDussen, Kelli L., Stappenbeck, Thaddeus S., Baldridge, Megan T., Sibley, L. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530208/
https://www.ncbi.nlm.nih.gov/pubmed/37384526
http://dx.doi.org/10.1016/j.celrep.2023.112680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530208/
https://www.ncbi.nlm.nih.gov/pubmed/37384526
http://dx.doi.org/10.1016/j.celrep.2023.112680

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