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Determination of the Diagnostic Performance of Laboratory Tests in the Absence of a Perfect Reference Standard: The Case of SARS-CoV-2 Tests

Background: Currently, assessing the diagnostic performance of new laboratory tests assumes a perfect reference standard, which is rarely the case. Wrong classifications of the true disease status will inevitably lead to biased estimates of sensitivity and specificity. Objectives: Using Bayesian’ la...

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Detalles Bibliográficos
Autores principales: Hartnack, Sonja, Nilius, Henning, Jegerlehner, Sabrina, Suter-Riniker, Franziska, Bittel, Pascal, Jent, Philipp, Nagler, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530219/
https://www.ncbi.nlm.nih.gov/pubmed/37761259
http://dx.doi.org/10.3390/diagnostics13182892