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Supramolecular multivalency effects enhance imine formation in aqueous medium allowing for dynamic modification of enzymatic activity
Imine formation under physiological conditions represents a challenging reaction due to the strong propensity of aldimines to be hydrolyzed. Herein we disclose the remarkable effect of supramolecular multivalency on increasing imine stability. A family of reactive aldehydes was synthesized bearing s...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530293/ https://www.ncbi.nlm.nih.gov/pubmed/37772124 http://dx.doi.org/10.1039/d3sc04128j |