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Single-Cell RNA-Sequencing Reveals Peripheral T Helper Cells Promoting the Development of IgG4-Related Disease by Enhancing B Cell Activation and Differentiation

Abnormal B cell differentiation plays a critical role in IgG4-related disease (IgG4-RD), but the underlying mechanism remains largely unknown. We investigated the cell landscape from three IgG4-RD retroperitoneal tissues and three control tissues using single-cell RNA-sequencing. Critical cell type...

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Detalles Bibliográficos
Autores principales: Ji, Zongfei, Lu, Weiqi, Wu, Sifan, Zhang, Yong, Meng, Dan, Zhang, Xiao, Dai, Xiaojuan, Chen, Huiyong, Ma, Lili, Sun, Ying, Jiang, Lindi, Kong, Xiufang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530310/
https://www.ncbi.nlm.nih.gov/pubmed/37762039
http://dx.doi.org/10.3390/ijms241813735