Organocatalyst-mediated, pot-economical total synthesis of latanoprost

The enantioselective total synthesis of latanoprost, an antiglaucoma agent, has been accomplished with excellent diastereo- and enantioselectivities in a pot-economical manner using six reaction vessels. An enantioselective Krische allylation was conducted in the first pot. In the second pot, olefin...

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Detalles Bibliográficos
Autores principales: Kawauchi, Genki, Suga, Yurina, Toda, Shunsuke, Hayashi, Yujiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530343/
https://www.ncbi.nlm.nih.gov/pubmed/37772091
http://dx.doi.org/10.1039/d3sc02978f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530343/
https://www.ncbi.nlm.nih.gov/pubmed/37772091
http://dx.doi.org/10.1039/d3sc02978f

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