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Organocatalyst-mediated, pot-economical total synthesis of latanoprost
The enantioselective total synthesis of latanoprost, an antiglaucoma agent, has been accomplished with excellent diastereo- and enantioselectivities in a pot-economical manner using six reaction vessels. An enantioselective Krische allylation was conducted in the first pot. In the second pot, olefin...
Autores principales: | Kawauchi, Genki, Suga, Yurina, Toda, Shunsuke, Hayashi, Yujiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530343/ https://www.ncbi.nlm.nih.gov/pubmed/37772091 http://dx.doi.org/10.1039/d3sc02978f |
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