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TERTmonitor—qPCR Detection of TERTp Mutations in Glioma

Telomerase promoter (TERTp) mutations are frequently observed in various types of tumours and commonly characterised by two specific hotspots located at positions −124 and −146 upstream of the start codon. They enhance TERTp activity, resulting in increased TERT expression. In central nervous system...

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Detalles Bibliográficos
Autores principales: Brás, João Paulo, Jesus, Tito Teles, Prazeres, Hugo, Lima, Jorge, Soares, Paula, Vinagre, João
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530400/
https://www.ncbi.nlm.nih.gov/pubmed/37761833
http://dx.doi.org/10.3390/genes14091693