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Fusobacterium nucleatum Load Correlates with KRAS Mutation and Sessile Serrated Pathogenesis in Colorectal Adenocarcinoma

Fusobacterium nucleatum (Fn) has been frequently detected in colorectal cancer. A high load of Fn has been associated with subtypes of colorectal cancers, located in the proximal colon, exhibiting microsatellite instability-high (MSI-H), MLH1 promoter hypermethylation, the CpG island hypermethylatio...

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Detalles Bibliográficos
Autores principales: Takeda, Koki, Koi, Minoru, Okita, Yoshiki, Sajibu, Sija, Keku, Temitope O., Carethers, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530411/
https://www.ncbi.nlm.nih.gov/pubmed/37772997
http://dx.doi.org/10.1158/2767-9764.CRC-23-0179