Angiotensin AT(1A) receptor signal switching in Agouti-related peptide neurons mediates metabolic rate adaptation during obesity

Resting metabolic rate (RMR) adaptation occurs during obesity and is hypothesized to contribute to failed weight management. Angiotensin II (Ang-II) type 1 (AT(1A)) receptors in Agouti-related peptide (AgRP) neurons contribute to the integrative control of RMR, and deletion of AT(1A) from AgRP neuro...

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Detalles Bibliográficos
Autores principales: Balapattabi, Kirthikaa, Yavuz, Yavuz, Jiang, Jingwei, Deng, Guorui, Mathieu, Natalia M., Ritter, McKenzie L., Opichka, Megan A., Reho, John J., McCorvy, John D., Nakagawa, Pablo, Morselli, Lisa L., Mouradian, Gary C., Atasoy, Deniz, Cui, Huxing, Hodges, Matthew R., Sigmund, Curt D., Grobe, Justin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530419/
https://www.ncbi.nlm.nih.gov/pubmed/37540598
http://dx.doi.org/10.1016/j.celrep.2023.112935

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530419/
https://www.ncbi.nlm.nih.gov/pubmed/37540598
http://dx.doi.org/10.1016/j.celrep.2023.112935

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