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Angiotensin AT(1A) receptor signal switching in Agouti-related peptide neurons mediates metabolic rate adaptation during obesity
Resting metabolic rate (RMR) adaptation occurs during obesity and is hypothesized to contribute to failed weight management. Angiotensin II (Ang-II) type 1 (AT(1A)) receptors in Agouti-related peptide (AgRP) neurons contribute to the integrative control of RMR, and deletion of AT(1A) from AgRP neuro...
Autores principales: | Balapattabi, Kirthikaa, Yavuz, Yavuz, Jiang, Jingwei, Deng, Guorui, Mathieu, Natalia M., Ritter, McKenzie L., Opichka, Megan A., Reho, John J., McCorvy, John D., Nakagawa, Pablo, Morselli, Lisa L., Mouradian, Gary C., Atasoy, Deniz, Cui, Huxing, Hodges, Matthew R., Sigmund, Curt D., Grobe, Justin L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530419/ https://www.ncbi.nlm.nih.gov/pubmed/37540598 http://dx.doi.org/10.1016/j.celrep.2023.112935 |
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