Force-induced motions of the PIEZO1 blade probed with fluorimetry

Mechanical forces are thought to activate mechanosensitive PIEZO channels by changing the conformation of a large transmembrane blade domain. Yet, whether different stimuli induce identical conformational changes in this domain remains unclear. Here, we repurpose a cyclic permuted green fluorescent...

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Detalles Bibliográficos
Autores principales: Ozkan, Alper D., Wijerathne, Tharaka D., Gettas, Tina, Lacroix, Jérôme J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530446/
https://www.ncbi.nlm.nih.gov/pubmed/37471225
http://dx.doi.org/10.1016/j.celrep.2023.112837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530446/
https://www.ncbi.nlm.nih.gov/pubmed/37471225
http://dx.doi.org/10.1016/j.celrep.2023.112837

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