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Force-induced motions of the PIEZO1 blade probed with fluorimetry
Mechanical forces are thought to activate mechanosensitive PIEZO channels by changing the conformation of a large transmembrane blade domain. Yet, whether different stimuli induce identical conformational changes in this domain remains unclear. Here, we repurpose a cyclic permuted green fluorescent...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530446/ https://www.ncbi.nlm.nih.gov/pubmed/37471225 http://dx.doi.org/10.1016/j.celrep.2023.112837 |