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Unfolded protein response factor ATF6 augments T helper cell responses and promotes mixed granulocytic airway inflammation
The unfolded protein response (UPR) is associated with the risk of asthma, including treatment-refractory severe asthma. Recent studies demonstrated a pathogenic role of activating transcription factor 6a (ATF6a or ATF6), an essential UPR sensor, in airway structural cells. However, its role in T he...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530451/ https://www.ncbi.nlm.nih.gov/pubmed/37209959 http://dx.doi.org/10.1016/j.mucimm.2023.05.007 |