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Unfolded protein response factor ATF6 augments T helper cell responses and promotes mixed granulocytic airway inflammation

The unfolded protein response (UPR) is associated with the risk of asthma, including treatment-refractory severe asthma. Recent studies demonstrated a pathogenic role of activating transcription factor 6a (ATF6a or ATF6), an essential UPR sensor, in airway structural cells. However, its role in T he...

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Detalles Bibliográficos
Autores principales: Wu, Dandan, Zhang, Xing, Zimmerly, Kourtney M., Wang, Ruoning, Wang, Chunqing, Hunter, Russell, Wu, Xiang, Campen, Matthew, Liu, Meilian, Yang, Xuexian O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530451/
https://www.ncbi.nlm.nih.gov/pubmed/37209959
http://dx.doi.org/10.1016/j.mucimm.2023.05.007