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Investigating Neuron Degeneration in Huntington’s Disease Using RNA-Seq Based Transcriptome Study
Huntington’s disease (HD) is a progressive neurodegenerative disorder caused due to a CAG repeat expansion in the huntingtin (HTT) gene. The primary symptoms of HD include motor dysfunction such as chorea, dystonia, and involuntary movements. The primary motor cortex (BA4) is the key brain region re...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530489/ https://www.ncbi.nlm.nih.gov/pubmed/37761940 http://dx.doi.org/10.3390/genes14091801 |