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Investigating Neuron Degeneration in Huntington’s Disease Using RNA-Seq Based Transcriptome Study

Huntington’s disease (HD) is a progressive neurodegenerative disorder caused due to a CAG repeat expansion in the huntingtin (HTT) gene. The primary symptoms of HD include motor dysfunction such as chorea, dystonia, and involuntary movements. The primary motor cortex (BA4) is the key brain region re...

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Detalles Bibliográficos
Autores principales: Sneha, Nela Pragathi, Dharshini, S. Akila Parvathy, Taguchi, Y.-h., Gromiha, M. Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530489/
https://www.ncbi.nlm.nih.gov/pubmed/37761940
http://dx.doi.org/10.3390/genes14091801