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Novel Conformation-Dependent Tau Antibodies Are Modulated by Adjacent Phosphorylation Sites

Tau proteins within the adult central nervous system (CNS) are found to be abnormally aggregated into heterogeneous filaments in neurodegenerative diseases, termed tauopathies. These tau inclusions are pathological hallmarks of Alzheimer’s disease (AD), Pick’s disease (PiD), corticobasal degeneratio...

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Detalles Bibliográficos
Autores principales: Paterno, Giavanna, Torrellas, Jose, Bell, Brach M., Gorion, Kimberly-Marie M., Quintin, Stephan S., Hery, Gabriela P., Prokop, Stefan, Giasson, Benoit I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530490/
https://www.ncbi.nlm.nih.gov/pubmed/37761979
http://dx.doi.org/10.3390/ijms241813676