Positive Allosteric Modulators of SERCA Pump Restore Dendritic Spines and Rescue Long-Term Potentiation Defects in Alzheimer’s Disease Mouse Model

Alzheimer’s disease (AD) is a neurodegenerative disorder that affects memory formation and storage processes. Dysregulated neuronal calcium (Ca(2+)) has been identified as one of the key pathogenic events in AD, and it has been suggested that pharmacological agents that stabilize Ca(2+) neuronal sig...

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Detalles Bibliográficos
Autores principales: Rakovskaya, Anastasiya, Erofeev, Alexander, Vinokurov, Egor, Pchitskaya, Ekaterina, Dahl, Russell, Bezprozvanny, Ilya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530588/
https://www.ncbi.nlm.nih.gov/pubmed/37762276
http://dx.doi.org/10.3390/ijms241813973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530588/
https://www.ncbi.nlm.nih.gov/pubmed/37762276
http://dx.doi.org/10.3390/ijms241813973

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