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Positive Allosteric Modulators of SERCA Pump Restore Dendritic Spines and Rescue Long-Term Potentiation Defects in Alzheimer’s Disease Mouse Model
Alzheimer’s disease (AD) is a neurodegenerative disorder that affects memory formation and storage processes. Dysregulated neuronal calcium (Ca(2+)) has been identified as one of the key pathogenic events in AD, and it has been suggested that pharmacological agents that stabilize Ca(2+) neuronal sig...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530588/ https://www.ncbi.nlm.nih.gov/pubmed/37762276 http://dx.doi.org/10.3390/ijms241813973 |