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Genomic Instability of G-Quadruplex Sequences in Escherichia coli: Roles of DinG, RecG, and RecQ Helicases

Guanine-rich DNA can fold into highly stable four-stranded DNA structures called G-quadruplexes (G4). Originally identified in sequences from telomeres and oncogene promoters, they can alter DNA metabolism. Indeed, G4-forming sequences represent obstacles for the DNA polymerase, with important conse...

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Detalles Bibliográficos
Autores principales: Parekh, Virali J., Węgrzyn, Grzegorz, Arluison, Véronique, Sinden, Richard R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530614/
https://www.ncbi.nlm.nih.gov/pubmed/37761860
http://dx.doi.org/10.3390/genes14091720