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Optical Detection of Distal Lung Enzyme Activity in Human Inflammatory Lung Disease

Objective and Impact Statement. There is a need to develop platforms delineating inflammatory biology of the distal human lung. We describe a platform technology approach to detect in situ enzyme activity and observe drug inhibition in the distal human lung using a combination of matrix metalloprote...

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Detalles Bibliográficos
Autores principales: Megia-Fernandez, Alicia, Marshall, Adam, Akram, Ahsan R., Mills, Bethany, Chankeshwara, Sunay V., Scholefield, Emma, Miele, Amy, McGorum, Bruce C., Michaels, Chesney, Knighton, Nathan, Vercauteren, Tom, Lacombe, Francois, Dentan, Veronique, Bruce, Annya M., Mair, Joanne, Hitchcock, Robert, Hirani, Nik, Haslett, Chris, Bradley, Mark, Dhaliwal, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAAS 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530652/
https://www.ncbi.nlm.nih.gov/pubmed/37851586
http://dx.doi.org/10.34133/2021/9834163