Adipocyte-Derived Small Extracellular Vesicles from Patients with Alzheimer Disease Carry miRNAs Predicted to Target the CREB Signaling Pathway in Neurons

Alzheimer disease (AD) is characterized by amyloid-β (Aβ) plaques, neurofibrillary tangles, synaptic dysfunction, and progressive dementia. Midlife obesity increases the risk of developing AD. Adipocyte-derived small extracellular vesicles (ad-sEVs) have been implicated as a mechanism in several obe...

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Detalles Bibliográficos
Autores principales: Batabyal, Rachael A., Bansal, Ankush, Cechinel, Laura Reck, Authelet, Kayla, Goldberg, Madeleine, Nadler, Evan, Keene, C. Dirk, Jayadev, Suman, Domoto-Reilly, Kimiko, Li, Gail, Peskind, Elaine, Hashimoto-Torii, Kazue, Buchwald, Dedra, Freishtat, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530811/
https://www.ncbi.nlm.nih.gov/pubmed/37762325
http://dx.doi.org/10.3390/ijms241814024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530811/
https://www.ncbi.nlm.nih.gov/pubmed/37762325
http://dx.doi.org/10.3390/ijms241814024

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