Effects of Early Exposure to Isoflurane on Susceptibility to Chronic Pain Are Mediated by Increased Neural Activity Due to Actions of the Mammalian Target of the Rapamycin Pathway

Patients who have undergone surgery in early life may be at elevated risk for suffering neuropathic pain in later life. The risk factors for this susceptibility are not fully understood. Here, we used a mouse chronic pain model to test the hypothesis that early exposure to the general anesthetic (GA...

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Detalles Bibliográficos
Autores principales: Li, Qun, Mathena, Reilley Paige, Li, Fengying, Dong, Xinzhong, Guan, Yun, Mintz, Cyrus David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530853/
https://www.ncbi.nlm.nih.gov/pubmed/37762067
http://dx.doi.org/10.3390/ijms241813760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530853/
https://www.ncbi.nlm.nih.gov/pubmed/37762067
http://dx.doi.org/10.3390/ijms241813760

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