Case Series of 11 CDH1 Families (47 Carriers) Including Incidental Findings, Signet Ring Cell Colon Cancer and Review of the Literature

Germline pathogenic variants in E-cadherin (CDH1) confer high risk of developing lobular breast cancer and diffuse gastric cancer (DGC). The cumulative risk of DGC in CDH1 carriers has been recently reassessed (from 40–83% by age 80 to 25–42%) and varies according to the presence and number of gastr...

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Detalles Bibliográficos
Autores principales: Lepage, Mathis, Uhrhammer, Nancy, Privat, Maud, Ponelle-Chachuat, Flora, Kossai, Myriam, Scanzi, Julien, Ouedraogo, Zangbéwendé Guy, Gay-Bellile, Mathilde, Bidet, Yannick, Cavaillé, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530895/
https://www.ncbi.nlm.nih.gov/pubmed/37761816
http://dx.doi.org/10.3390/genes14091677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530895/
https://www.ncbi.nlm.nih.gov/pubmed/37761816
http://dx.doi.org/10.3390/genes14091677

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