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Biomolecular interactions studied by low-field NMR using SABRE hyperpolarization

We demonstrate that low-field nuclear magnetic resonance provides a means for measuring biomacromolecular interactions without requiring a superconducting, or even a permanent magnet. A small molecule, 5-fluoropyridine-3-carboximidamide, is designed to be a specific ligand for the trypsin protein, w...

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Detalles Bibliográficos
Autores principales: Pham, Pierce, Hilty, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530938/
https://www.ncbi.nlm.nih.gov/pubmed/37772094
http://dx.doi.org/10.1039/d3sc02365f