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Persistent Molecular Disease in Adult Patients With AML Evaluated With Whole-Exome and Targeted Error-Corrected DNA Sequencing

PURPOSE: Persistent molecular disease (PMD) after induction chemotherapy predicts relapse in AML. In this study, we used whole-exome sequencing (WES) and targeted error-corrected sequencing to assess the frequency and mutational patterns of PMD in 30 patients with AML. MATERIALS AND METHODS: The stu...

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Detalles Bibliográficos
Autores principales: Slade, Michael J., Ghasemi, Reza, O'Laughlin, Michelle, Burton, Tasha, Fulton, Robert S., Abel, Haley J., Duncavage, Eric J., Ley, Timothy J., Jacoby, Meagan A., Spencer, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530963/
https://www.ncbi.nlm.nih.gov/pubmed/37079859
http://dx.doi.org/10.1200/PO.22.00559