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Effect of Combined Levothyroxine (L-T(4)) and 3-Iodothyronamine (T(1)AM) Supplementation on Memory and Adult Hippocampal Neurogenesis in a Mouse Model of Hypothyroidism

Mood alterations, anxiety, and cognitive impairments associated with adult-onset hypothyroidism often persist despite replacement treatment. In rodent models of hypothyroidism, replacement does not bring 3-iodothyronamine (T(1)AM) brain levels back to normal. T(1)AM is a thyroid hormone derivative w...

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Detalles Bibliográficos
Autores principales: Rutigliano, Grazia, Bertolini, Andrea, Grittani, Nicoletta, Frascarelli, Sabina, Carnicelli, Vittoria, Ippolito, Chiara, Moscato, Stefania, Mattii, Letizia, Kusmic, Claudia, Saba, Alessandro, Origlia, Nicola, Zucchi, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530993/
https://www.ncbi.nlm.nih.gov/pubmed/37762153
http://dx.doi.org/10.3390/ijms241813845