Cargando…
Effect of Combined Levothyroxine (L-T(4)) and 3-Iodothyronamine (T(1)AM) Supplementation on Memory and Adult Hippocampal Neurogenesis in a Mouse Model of Hypothyroidism
Mood alterations, anxiety, and cognitive impairments associated with adult-onset hypothyroidism often persist despite replacement treatment. In rodent models of hypothyroidism, replacement does not bring 3-iodothyronamine (T(1)AM) brain levels back to normal. T(1)AM is a thyroid hormone derivative w...
Autores principales: | Rutigliano, Grazia, Bertolini, Andrea, Grittani, Nicoletta, Frascarelli, Sabina, Carnicelli, Vittoria, Ippolito, Chiara, Moscato, Stefania, Mattii, Letizia, Kusmic, Claudia, Saba, Alessandro, Origlia, Nicola, Zucchi, Riccardo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10530993/ https://www.ncbi.nlm.nih.gov/pubmed/37762153 http://dx.doi.org/10.3390/ijms241813845 |
Ejemplares similares
-
Endogenous 3-Iodothyronamine (T1AM) and Synthetic Thyronamine-Like Analog SG-2 Act as Novel Pleiotropic Neuroprotective Agents through the Modulation of SIRT6
por: Bellusci, Lorenza, et al.
Publicado: (2020) -
Metabolic Reprogramming by 3-Iodothyronamine (T1AM): A New Perspective to Reverse Obesity through Co-Regulation of Sirtuin 4 and 6 Expression
por: Assadi-Porter, Fariba M., et al.
Publicado: (2018) -
Modulation of cardiac ionic homeostasis by 3-iodothyronamine
por: Ghelardoni, Sandra, et al.
Publicado: (2009) -
T1AM/TAAR1 System Reduces Inflammatory Response and β-Amyloid Toxicity in Human Microglial HMC3 Cell Line
por: Polini, Beatrice, et al.
Publicado: (2023) -
Modulation of Gene Expression by 3-Iodothyronamine: Genetic Evidence for a Lipolytic Pattern
por: Mariotti, Veronica, et al.
Publicado: (2014)