Redox-Sensitive Delivery of Doxorubicin from Nanoparticles of Poly(ethylene glycol)-Chitosan Copolymer for Treatment of Drug-Resistant Oral Cancer Cells

Reactive oxygen species (ROS)-sensitive polymer nanoparticles were synthesized for tumor targeting of an anticancer drug, doxorubicin (DOX). For this purpose, chitosan-methoxy poly(ethylene glycol) (mPEG) (ChitoPEG)-graft copolymer was synthesized and then DOX was conjugated to the backbone of chito...

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Detalles Bibliográficos
Autores principales: Yoon, Kaengwon, Jung, Seunggon, Ryu, Jaeyoung, Park, Hong-Ju, Oh, Hee-Kyun, Kook, Min-Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531032/
https://www.ncbi.nlm.nih.gov/pubmed/37762003
http://dx.doi.org/10.3390/ijms241813704

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531032/
https://www.ncbi.nlm.nih.gov/pubmed/37762003
http://dx.doi.org/10.3390/ijms241813704

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