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Redox-Sensitive Delivery of Doxorubicin from Nanoparticles of Poly(ethylene glycol)-Chitosan Copolymer for Treatment of Drug-Resistant Oral Cancer Cells
Reactive oxygen species (ROS)-sensitive polymer nanoparticles were synthesized for tumor targeting of an anticancer drug, doxorubicin (DOX). For this purpose, chitosan-methoxy poly(ethylene glycol) (mPEG) (ChitoPEG)-graft copolymer was synthesized and then DOX was conjugated to the backbone of chito...
Autores principales: | Yoon, Kaengwon, Jung, Seunggon, Ryu, Jaeyoung, Park, Hong-Ju, Oh, Hee-Kyun, Kook, Min-Suk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531032/ https://www.ncbi.nlm.nih.gov/pubmed/37762003 http://dx.doi.org/10.3390/ijms241813704 |
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