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Blocking CCN2 Reduces Established Palmar Neuromuscular Fibrosis and Improves Function Following Repetitive Overuse Injury

The matricellular protein cell communication factor 2/connective tissue growth factor (CCN2/CTGF) is critical to development of neuromuscular fibrosis. Here, we tested whether anti-CCN2 antibody treatment will reduce established forepaw fibro-degenerative changes and improve function in a rat model...

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Detalles Bibliográficos
Autores principales: Lambi, Alex G., DeSante, Robert J., Patel, Parth R., Hilliard, Brendan A., Popoff, Steven N., Barbe, Mary F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531056/
https://www.ncbi.nlm.nih.gov/pubmed/37762168
http://dx.doi.org/10.3390/ijms241813866