Droplet Digital PCR Is a Novel Screening Method Identifying Potential Cardiac G-Protein-Coupled Receptors as Candidate Pharmacological Targets in a Rat Model of Pressure-Overload-Induced Cardiac Dysfunction

The identification of novel drug targets is needed to improve the outcomes of heart failure (HF). G-protein-coupled receptors (GPCRs) represent the largest family of targets for already approved drugs, thus providing an opportunity for drug repurposing. Here, we aimed (i) to investigate the differen...

Descripción completa

Detalles Bibliográficos
Autores principales: Sayour, Nabil V., Tóth, Viktória É., Nagy, Regina N., Vörös, Imre, Gergely, Tamás G., Onódi, Zsófia, Nagy, Noémi, Bödör, Csaba, Váradi, Barnabás, Ruppert, Mihály, Radovits, Tamás, Bleckwedel, Federico, Zelarayán, Laura C., Pacher, Pal, Ágg, Bence, Görbe, Anikó, Ferdinandy, Péter, Varga, Zoltán V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531061/
https://www.ncbi.nlm.nih.gov/pubmed/37762130
http://dx.doi.org/10.3390/ijms241813826

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531061/
https://www.ncbi.nlm.nih.gov/pubmed/37762130
http://dx.doi.org/10.3390/ijms241813826

Ejemplares similares