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Tetraploidization Increases the Motility and Invasiveness of Cancer Cells

Polyploidy and metastasis are associated with a low probability of disease-free survival in cancer patients. Polyploid cells are known to facilitate tumorigenesis. However, few data associate polyploidization with metastasis. Here, by generating and using diploid (2n) and tetraploid (4n) clones from...

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Detalles Bibliográficos
Autores principales: Jemaà, Mohamed, Daams, Renee, Charfi, Slim, Mertens, Fredrik, Huber, Stephan M., Massoumi, Ramin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531202/
https://www.ncbi.nlm.nih.gov/pubmed/37762227
http://dx.doi.org/10.3390/ijms241813926