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Isothiocyanates as Tubulin Polymerization Inhibitors—Synthesis and Structure–Activity Relationship Studies

Among the various substances that interfere with the microtubule formation process, isothiocyanates (ITCs) are the group of compounds for which the binding mode and mechanism of action have not yet been explained. To better understand the structure–activity relationship of tubulin-isothiocyanate int...

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Detalles Bibliográficos
Autores principales: Grzywa, Renata, Psurski, Mateusz, Gajda, Anna, Gajda, Tadeusz, Janczewski, Łukasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531289/
https://www.ncbi.nlm.nih.gov/pubmed/37761977
http://dx.doi.org/10.3390/ijms241813674