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The Intergeneration Long-Lasting Consequences of Pre-Conceptional Exposure to Sofosbuvir on the Ovarian Tissues of F1 Offspring: Experimental Study on Rats

Sofosbuvir (SOF), a nucleos(t)ide polymerase inhibitor, has been used during the past decade for mass treatment of viral hepatitis C in endemic countries like Egypt, increasing the exposure of women at childbearing age to SOF. This study investigated the long-lasting consequences of the pre-concepti...

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Detalles Bibliográficos
Autores principales: Hafez, Hala A., Mahmoud, Shimaa A., Alhmoud, Jehad F., Khafaga, Rana H.M., Kamel, Maher A., Shaker, Sara A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531293/
https://www.ncbi.nlm.nih.gov/pubmed/37761983
http://dx.doi.org/10.3390/ijms241813675