Interaction Analysis Reveals Complex Genetic Associations with Alzheimer’s Disease in the CLU and ABCA7 Gene Regions

Sporadic Alzheimer’s disease (AD) is a polygenic neurodegenerative disorder. Single-nucleotide polymorphisms (SNPs) in multiple genes (e.g., CLU and ABCA7) have been associated with AD. However, none of them were characterized as causal variants that indicate the complex genetic architecture of AD,...

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Detalles Bibliográficos
Autores principales: Nazarian, Alireza, Cook, Brandon, Morado, Marissa, Kulminski, Alexander M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531324/
https://www.ncbi.nlm.nih.gov/pubmed/37761806
http://dx.doi.org/10.3390/genes14091666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531324/
https://www.ncbi.nlm.nih.gov/pubmed/37761806
http://dx.doi.org/10.3390/genes14091666

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