Hardening of Respiratory Syncytial Virus Inclusion Bodies by Cyclopamine Proceeds through Perturbation of the Interactions of the M2-1 Protein with RNA and the P Protein

Respiratory syncytial virus (RSV) RNA synthesis takes place in cytoplasmic viral factories also called inclusion bodies (IBs), which are membrane-less organelles concentrating the viral RNA polymerase complex. The assembly of IBs is driven by liquid-liquid phase separation promoted by interactions b...

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Detalles Bibliográficos
Autores principales: Diot, Cédric, Richard, Charles-Adrien, Risso-Ballester, Jennifer, Martin, Davy, Fix, Jenna, Eléouët, Jean-François, Sizun, Christina, Rameix-Welti, Marie-Anne, Galloux, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531356/
https://www.ncbi.nlm.nih.gov/pubmed/37762166
http://dx.doi.org/10.3390/ijms241813862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531356/
https://www.ncbi.nlm.nih.gov/pubmed/37762166
http://dx.doi.org/10.3390/ijms241813862

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