Exploring the Syndecan-Mediated Cellular Internalization of the SARS-CoV-2 Omicron Variant

SARS-CoV-2 variants evolve to rely more on heparan sulfate (HS) for viral attachment and subsequent infection. In our earlier work, we demonstrated that the Delta variant’s spike protein binds more strongly to HS compared to WT SARS-CoV-2, leading to enhanced cell internalization via syndecans (SDCs...

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Detalles Bibliográficos
Autores principales: Letoha, Annamária, Hudák, Anett, Letoha, Tamás
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531417/
https://www.ncbi.nlm.nih.gov/pubmed/37762442
http://dx.doi.org/10.3390/ijms241814140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10531417/
https://www.ncbi.nlm.nih.gov/pubmed/37762442
http://dx.doi.org/10.3390/ijms241814140

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